Ira Kurtz Selected Research

Sodium-Bicarbonate Symporters

1/2018	CryoEM structure of the human SLC4A4 sodium-coupled acid-base transporter NBCe1.
3/2013	Topology of NBCe1 protein transmembrane segment 1 and structural effect of proximal renal tubular acidosis (pRTA) S427L mutation.
9/2008	G418-mediated ribosomal read-through of a nonsense mutation causing autosomal recessive proximal renal tubular acidosis.
11/2005	Time course of auditory impairment in mice lacking the electroneutral sodium bicarbonate cotransporter NBC3 (slc4a7).
7/2003	Blindness and auditory impairment caused by loss of the sodium bicarbonate cotransporter NBC3.

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Ira Kurtz Research Topics

Disease

7	Renal Tubular Acidosis (Distal Renal Tubular Acidosis) 01/2021 - 09/2008
7	Acidosis 01/2018 - 06/2005
4	Thrombotic Microangiopathies 10/2021 - 01/2019
4	Hypertension (High Blood Pressure) 12/2020 - 06/2005
4	Hyponatremia 01/2020 - 06/2004
3	Inappropriate ADH Syndrome (SIADH) 01/2020 - 06/2003
3	Neoplasms (Cancer) 01/2019 - 02/2007
2	Proteinuria 12/2020 - 01/2020
2	Edema (Dropsy) 01/2020 - 08/2007
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2020 - 01/2019
2	Hemolysis 01/2019 - 01/2019
2	Atypical Hemolytic Uremic Syndrome 01/2019 - 01/2019
2	Hypokalemia 01/2018 - 06/2004
2	Blindness (Hysterical Blindness) 01/2018 - 07/2003
2	Ketosis 01/2008 - 06/2006
2	Hyperglycemia 01/2005 - 08/2004
1	Macular Degeneration (Age-Related Maculopathy) 10/2021
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2021
1	Segmental glomerulosclerosis 12/2020
1	Weight Gain 10/2020
1	Diabetic Nephropathies (Diabetic Nephropathy) 01/2020
1	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2020
1	Exanthema (Rash) 01/2020
1	Fuchs' Endothelial Dystrophy 01/2020
1	Interstitial Nephritis (Tubulointerstitial Nephritis) 01/2020
1	Membranoproliferative Glomerulonephritis (Membranoproliferative Glomerulonephritis, Type II) 01/2020
1	Disease Progression 01/2020
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2020
1	Acute Kidney Injury (Acute Renal Failure) 01/2020
1	Thrombotic Thrombocytopenic Purpura 01/2019
1	Hemolytic-Uremic Syndrome 01/2019
1	1 Posterior Polymorphous Corneal Dystrophy 01/2019
1	Ulcerative Colitis 01/2019
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2019
1	Vitamin B 12 Deficiency (Vitamin B12 Deficiency) 01/2019
1	Crohn Disease (Crohn's Disease) 01/2019
1	Migraine Disorders (Migraine) 01/2018
1	Hypercalciuria 01/2018
1	Hepatocellular Carcinoma (Hepatoma) 01/2018
1	Nephrocalcinosis 01/2018
1	Diarrhea 02/2015
1	Shock 02/2015
1	Hypovolemia 02/2015
1	Fibrosis (Cirrhosis) 07/2014
1	Hypoalbuminemia 07/2014
1	Confusion (Bewilderment) 08/2011
1	Intellectual Disability (Idiocy) 09/2008
1	Glaucoma 09/2008
1	Cataract (Cataracts) 09/2008

Drug/Important Bio-Agent (IBA)

5	Sodium-Bicarbonate SymportersIBA 01/2018 - 07/2003
5	Bicarbonates (Hydrogen Carbonate)IBA 02/2015 - 06/2005
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2021 - 01/2019
4	Proteins (Proteins, Gene)FDA Link 01/2020 - 06/2006
3	Pharmaceutical PreparationsIBA 01/2021 - 01/2019
3	Complement System Proteins (Complement)IBA 01/2020 - 01/2019
3	Vasopressins (Vasopressin)IBA 01/2020 - 03/2003
3	SodiumIBA 01/2020 - 06/2003
2	CalciumIBA 01/2021 - 02/2015
2	Antigen-Antibody Complex (Immune Complex)IBA 01/2020 - 01/2020
2	AcidsIBA 02/2015 - 06/2005
2	Nonsense Codon (Nonsense Mutation)IBA 04/2010 - 09/2008
2	Glucose (Dextrose)FDA LinkGeneric 01/2005 - 08/2004
1	FructoseIBA 10/2020
1	Adenosine Triphosphate (ATP)IBA 01/2020
1	Bevacizumab (Avastin)FDA Link 01/2020
1	Ranibizumab (Lucentis)FDA Link 01/2020
1	Tolvaptan FDA Link 01/2020
1	Adenosine Triphosphatases (ATPase)IBA 01/2020
1	Amiodarone (Amiodarona)FDA LinkGeneric 01/2020
1	Chlorthalidone (Chlortalidone)FDA LinkGeneric 01/2020
1	DNA (Deoxyribonucleic Acid)IBA 01/2020
1	SNARE Proteins (SNAREs)IBA 01/2020
1	SLC4A ProteinsIBA 01/2020
1	ThrombospondinsIBA 01/2019
1	Mercaptopurine (6 Mercaptopurine)FDA LinkGeneric 01/2019
1	Biological ProductsIBA 01/2019
1	Shiga Toxin (Shigella Toxin)IBA 01/2019
1	Metalloproteases (Metalloproteinases)IBA 01/2019
1	eculizumab FDA Link 01/2019
1	Complement C5 (Complement 5)IBA 01/2019
1	DisintegrinsIBA 01/2019
1	aminoacylase I (aminoacylase)IBA 01/2018
1	EnzymesIBA 01/2018
1	AmmoniaIBA 01/2018
1	ChloridesIBA 02/2015
1	Carbon DioxideIBA 02/2015
1	AlbuminsIBA 07/2014
1	Peptides (Polypeptides)IBA 12/2011
1	Protons (Proton)IBA 08/2011
1	Methanol (Carbinol)IBA 01/2008
1	2-Propanol (Isopropyl Alcohol)FDA LinkGeneric 01/2008
1	Ethylene Glycol (Monoethylene Glycol)IBA 01/2008
1	diethylene glycolIBA 01/2008
1	Propylene Glycol (1,2 Propanediol)FDA LinkGeneric 01/2008
1	Valacyclovir (Valtrex)FDA LinkGeneric 02/2007
1	Allopurinol (Remid)FDA LinkGeneric 02/2007

Therapy/Procedure

7	Therapeutics 01/2020 - 06/2003
1	Fecal Microbiota Transplantation 10/2020
1	Transplantation 01/2020
1	Penetrating Keratoplasty 08/2007